α-dystroglycan (IIH6) Antibody sc-53987 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemα-dystroglycan (IIH6) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Numbersc-53987
Antibody TypePrimary Antibodies
NCBI Gene AliasesDAG, Dp427, MDDGA9, 156DAG, AGRNR, D9Wsu13e, A3a, Dp71, MDDGC9, DG, MDDGC7, LGMDR16
CloneIIH6
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human, rabbit, canine
Hostmouse
Conjugate/TagUnconjugated
ClonalityMonoclonal
FormatPurified
NCBI Full Gene Namedystroglycan 1
Targetalpha-dystroglycan
IsotypeIgM

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Deletion of the first glycosylation site promotes Lassa virus glycoprotein-mediated membrane fusionVirologica SinicaJune 1, 2023Siqi Dong, Wenting Mao, Yang Liu, Xiaoying Jia, Yueli Zhang, Minmin Zhou, Yuxia Hou, Gengfu Xiao, Wei Wangdeterminations. 2.5 Binding assay A549 cells were pretreated with 200 μg/mL monoclonal antibody IIH6 (sc-53987; Santa Cruz Biotechnology, Dallas, TX, USA) or IgM (sc-53347; Santa Cruz Biotechnology) control at 37

(2) Screening and Identification of Lassa Virus Entry Inhibitors from a Fragment-Based Drug Discovery LibraryVirusesNovember 27, 2022Yuxia Hou, Yang Liu, Xiaoying Jia, Minmin Zhou, Wenting Mao, Siqi Dong, Yueli Zhang, Gengfu Xiao, Wei WangμM, 200 μM) at 37 °C for 1 h. As a control, A549 cells were pretreated either with 200 μg/mL IIH6 (sc-53987; Santa Cruz Biotechnology, Dallas, TX, USA) or a control IgM (50 μg/mL) at 4 °C for 1 h. The cells were

(3) CD164 is a host factor for lymphocytic choriomeningitis virus entryProceedings of the National Academy of Sciences of the United States of AmericaMarch 8, 2022Bakkers MJG, Moon-Walker A, Herlo R, Brusic V, Stubbs SH, Hastie KM, Saphire EO, Kirchhausen TL, Whelan SPJ.expression was further confirmed by flow cytometry using antibody IIH6 (Santa Cruz Biotechnology No. sc-53987). SLC35A1 and ST3GAL4 knockouts were confirmed by genomic DNA analysis. Genome-Wide CRISPR-Cas9 Screen. To

(4) Sertoli Cells Improve Myogenic Differentiation, Reduce Fibrogenic Markers, and Induce Utrophin Expression in Human DMD MyoblastsBiomoleculesOctober 12, 2021Salvadori L, Chiappalupi S, Arato I, Mancuso F, Calvitti M, Marchetti MC, Riuzzi F, Calafiore R, Luca G, Sorci G.IgG from rabbit serum,Sigma-Aldrich,Cat#I5006 Mouse monoclonal anti- α-Dystroglycan (IIH6),Santa Cruz Biotechnology,Cat# sc-53987 Mouse monoclonal anti-Myogenin (F5D),Santa Cruz Biotechnology,Cat#sc-12735 Mouse monoclonal anti-Utrophin (8A4

(5) Screening of Botanical Drugs against Lassa Virus EntryJournal of VirologyMarch 25, 2021Yang Liu, Jiao Guo, Junyuan Cao, Guangshun Zhang, Xiaoying Jia, Peilin Wang, Gengfu Xiao, Wei Wangbergamottin or 25 μM casticin at 37°C for 1 h. As a control, A549 cells were pretreated either with IIH6 (sc-53987; Santa Cruz Biotechnology, Dallas, TX, USA) or a control IgM at 4°C for 2 h (15, 16). The cells were

(6) Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse modelsScience advancesFebruary 1, 2020Yu L, Zhang X, Yang Y, Li D, Tang K, Zhao Z, He W, Wang C, Sahoo N, Converso-Baran K, et al.anti-LC3 (L8918, Sigma), anti-dystrophin (ab15277, Abcam), anti-utrophin (8A4, DSHB), anti–α-dystroglycan (sc-53987, Santa Cruz Biotechnology), and anti-GAPDH (glyceraldehyde 3-phosphate dehydrogenase) (MAB347, Millipore).

(7) Functional and cellular localization diversity associated with Fukutin-related protein patient genetic variantsHuman mutationOctober 1, 2019Henriques SF, Gicquel E, Marsolier J, Richard I.BD-Biosciences), iew 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 Human Mutation TGN46 (Sheep, AHP500GT, BioRad), α-dystroglycan (IIH6; Mouse, sc-53987, Santa Cruz Biotechnology), β-integrin (Mouse, sc-13590, Santa Cruz Biotechnology) or Wheat Germ Agglutinin

(8) M. leprae interacts with the human epidermal keratinocytes, neonatal (HEKn) via the binding of laminin-5 with α-dystroglycan, integrin-β1, or -β4PLOS Neglected Tropical DiseasesJune 24, 2019Song-Hyo Jin, Se-Kon Kim, Seong-Beom Lee(Cambridge, MA). Antibodies against LN-α2 (sc-55605 for immunohistochemistry), α-dystroglycan (α-DG, sc-53987 for immunocytochemistry and binding assays), integrin-β2 (sc-13548 for binding assays) and–β3 (sc-52589

(9) Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathyJCI InsightJune 6, 2019Michelle S. Parvatiyar et al.Development Studies Hybridoma Bank); utrophin (MANCHO3) (1:5; Development Studies Hybridoma Bank); α-DG IIH6 (sc-53987) (1:500; Santa Cruz Biotechnology Inc.); α-DG core (45-3, 1:5 serum-free fraction) (53); β-DG (MANDAG2)

(10) Screening and Identification of Lassa Virus Entry Inhibitors from an FDA-Approved Drug LibraryJournal of VirologyAugust 15, 2018Peilin Wang, Yang Liu, Guangshun Zhang, Shaobo Wang, Jiao Guo, Junyuan Cao, Xiaoying Jia, Leike Zhang, Gengfu Xiao, Wei Wanglacidipine or phenothrin at 37°C for 1 h. As a control, Vero cells were pretreated with 200 ␮g/ml IIH6 (sc-53987; Santa Cruz) or a control IgM at 4°C for 2 h in parallel (37, 39). Then, the cells were transferred

(11) A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9Disease Models & MechanismsJune 1, 2018Tingting Sui, Yeh Siang Lau, Di Liu, Tingjun Liu, Li Xu, Yandi Gao, Liangxue Lai, Zhanjun Li, Renzhi Hanagainst dystrophin (MANDYS1 clone 3B7, 1:20, Developmental Studies Hybridoma Bank), α-dystroglycan (sc-53987, 1:50, Santa Cruz Biotechnology), α-sarcoglycan (NCL-L-a-SARC, 1:100, Leica Biosystems) and caveolin

(12) High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMDHuman Molecular GeneticsOctober 24, 2016Elizabeth M. Gibbs, Jamie L. Marshall, Eva Ma, Thien M. Nguyen, Grace Hong, Jessica S. Lam, Melissa J. Spencer, Rachelle H. Crosbie-Watsonwith the following primary antibodies: dystrophin (MANDYS1; 1:5), utrophin (MANCHO3; 1:50), α-DG IIH6 (sc-53987; 1:500; Santa Cruz Biotechnology, Inc.), β-DG (MANDAG2; 1:250), α-SG (VP-A105; 1:100), β-SG (VP-B206;

(13) Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy–Associated CardiomyopathyJournal of the American Heart AssociationDecember 23, 2015Michelle S. Parvatiyar, Jamie L. Marshall, Reginald T. Nguyen, Maria C. Jordan, Vanitra A. Richardson, Kenneth P. Roos, Rachelle H. Crosbie‐WatsonDevelopment Studies Hybridoma Bank), Utr (MANCHO3, 1:50; Development Studies Hybridoma Bank), α‐DG IIH6 (sc‐53987, 1:500; Santa Cruz Biotechnology, Inc), β‐DG (MANDAG2, 1:250; Development Studies Hybridoma Bank), α‐SG

(14) Sarcospan-dependent Akt activation is required for utrophin expression and muscle regenerationThe Journal of cell biologyJune 25, 2012Marshall JL, Holmberg J, Chou E, Ocampo AC, Oh J, Lee J, Peter AK, Martin PT, Crosbie-Watson RH.with the following primary antibodies: dystrophin (MANDYS1; 1:2), utrophin (MANCHO3; 1:50), α-DG IIH6 (sc-53987; 1:500; Santa Cruz Biotechnology, Inc.), β-DG (MANDAG2; 1:250), α-SG (VP-A105; 1:100), β-SG (VP-B206;

(15) α-Dystroglycan is essential for the induction of Egr3, a transcription factor important in muscle spindle formationDevelopmental NeurobiologyMarch 10, 2010Stacey Williams, Christian Jacobsonprepared at this time. 2.2.2 Blocking experiments α-DG was blocked with the monoclonal antibody 11H6 (sc-53987; Santa Cruz Biotechnology, Santa Cruz, CA). This antibody was added to C2C12 myotubes one hour prior

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α-dystroglycan (IIH6) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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α-dystroglycan (IIH6) Antibody from Santa Cruz Biotechnology, Inc.

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